Hypoxia Shapes Autophagy in LPS-Activated Dendritic Cells

Hypoxia Shapes Autophagy in LPS-Activated Dendritic Cells

During their lifespan, dendritic cells (DCs) are exposed to different pO2 levels that affect their differentiation and functions. Autophagy is one of the adaptive responses to hypoxia with important implications for cell survival. While the autophagic machinery in DCs was shown to impact signaling o...

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Bibliographic Details
Main Authors: Sara Monaci, Carlo Aldinucci, Daniela Rossi, Gaia Giuntini, Irene Filippi, Cristina Ulivieri, Giuseppe Marotta, Silvano Sozzani, Fabio Carraro, Antonella Naldini
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Immunology
Subjects:
hypoxia
dendritic cell
autophagy
(macroautophagy)
hypoxia-inducible factor (HIF)-1α
lipopolysaccharide (LPS)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.573646/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.573646/full

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