Mediator complex interaction partners organize the transcriptional network that defines neural stem cells
The Mediator complex regulates transcription by connecting enhancers to promoters. Here, the authors purify Mediator from neural stem cells (NSCs), identify 75 novel protein-protein interaction partners and characterize the Mediator-interacting network that regulates transcription and establishes NS...
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-06-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-10502-8 |