Wnt/β-catenin Signaling Pathway Regulates Specific lncRNAs That Impact Dermal Fibroblasts and Skin Fibrosis

Wnt/β-catenin Signaling Pathway Regulates Specific lncRNAs That Impact Dermal Fibroblasts and Skin Fibrosis

Wnt/β-catenin signaling is required for embryonic dermal fibroblast cell fate, and dysregulation of this pathway is sufficient to promote fibrosis in adult tissue. The downstream modulators of Wnt/β-catenin signaling required for controlling cell fate and dermal fibrosis remain poorly understood. Th...

Full description

Bibliographic Details
Main Authors: Nathaniel K. Mullin, Nikhil V. Mallipeddi, Emily Hamburg-Shields, Beatriz Ibarra, Ahmad M. Khalil, Radhika P. Atit
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Genetics
Subjects:
gene expression
Mmp10
Wincr1
Wincr2
dermis
development
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2017.00183/full

Internet

http://journal.frontiersin.org/article/10.3389/fgene.2017.00183/full

Similar Items