Amifostine ameliorates cerebral ischaemia-reperfusion injury via p38-mediated oxidative stress and mitochondrial dysfunction

Amifostine ameliorates cerebral ischaemia-reperfusion injury via p38-mediated oxidative stress and mitochondrial dysfunction

Amifostine is a cytoprotective compound that is beneficial in ischaemic stroke cases. However, the neuroprotective effect of amifostine on ischaemia/reperfusion (I/R)-induced brain injury and its underlying mechanism are still poorly understood. Herein, we constructed an animal model of middle cereb...

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Bibliographic Details
Main Authors: Huifeng Cheng, Miaojun Lv, Rulin Mi, Guofang Xue
Format: Article
Language:English
Published: Termedia Publishing House 2021-01-01
Series:Folia Neuropathologica
Subjects:
amifostine
ischaemia-reperfusion injury
brain
mitochondrial dysfunction
neuron.
Online Access:https://www.termedia.pl/Amifostine-ameliorates-cerebral-ischaemia-reperfusion-injury-r-nvia-p38-mediated-oxidative-stress-and-mitochondrial-dysfunction,20,42964,1,1.html

Internet

https://www.termedia.pl/Amifostine-ameliorates-cerebral-ischaemia-reperfusion-injury-r-nvia-p38-mediated-oxidative-stress-and-mitochondrial-dysfunction,20,42964,1,1.html

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