The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism

Cancer: Interplay between histone modification and tumor metabolism Genes involved in the removal of methyl groups from histones associated with DNA can promote or suppress tumor growth depending on the metabolic status of the cancer cell. Hyunsung Park and colleagues at the University of Seoul, Sou...

Full description

Bibliographic Details
Main Authors: Soojeong Chang, Sujin Yim, Hyunsung Park
Format: Article
Language:English
Published: Nature Publishing Group 2019-06-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-019-0230-6