Nutritional Heterogeneity Among Aspergillus fumigatus Strains Has Consequences for Virulence in a Strain- and Host-Dependent Manner

Nutritional Heterogeneity Among Aspergillus fumigatus Strains Has Consequences for Virulence in a Strain- and Host-Dependent Manner

Acquisition and subsequent metabolism of different carbon and nitrogen sources have been shown to play an important role in virulence attributes of the fungal pathogen Aspergillus fumigatus, such as the secretion of host tissue-damaging proteases and fungal cell wall integrity. We examined the relat...

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Bibliographic Details
Main Authors: Laure Nicolas Annick Ries, Jacob L. Steenwyk, Patrícia Alves de Castro, Pollyne Borborema Almeida de Lima, Fausto Almeida, Leandro José de Assis, Adriana Oliveira Manfiolli, Azusa Takahashi-Nakaguchi, Yoko Kusuya, Daisuke Hagiwara, Hiroki Takahashi, Xi Wang, Joshua J. Obar, Antonis Rokas, Gustavo H. Goldman
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Microbiology
Subjects:
Aspergillus fumigatus
clinical isolates
carbon and nitrogen catabolite repression
genome comparison
cell wall
virulence
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00854/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.00854/full

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