Capturing Amyloid-β Oligomers by Stirring with Microscaled Iron Oxide Stir Bars into Magnetic Plaques to Reduce Cytotoxicity toward Neuronal Cells

Capturing Amyloid-β Oligomers by Stirring with Microscaled Iron Oxide Stir Bars into Magnetic Plaques to Reduce Cytotoxicity toward Neuronal Cells

Soluble amyloid-β oligomers (oAβ<sub>42</sub>)-induced neuronal death and inflammation response has been recognized as one of the major causes of Alzheimer’s disease (AD). In this work, a novel strategy adopting silica-coated iron oxide stir bar (MSB)-based AD therapy system via magnetic...

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Bibliographic Details
Main Authors: Yuan-Chung Tsai, Jing-Chian Luo, Te-I Liu, I-Lin Lu, Ming-Yin Shen, Chun-Yu Chuang, Chorng-Shyan Chern, Hsin-Cheng Chiu
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Nanomaterials
Subjects:
Alzheimer’s disease
amyloid beta-peptides
microglial cell polarization
microscaled stirring
magnetic stir bars
Online Access:https://www.mdpi.com/2079-4991/10/7/1284

Internet

https://www.mdpi.com/2079-4991/10/7/1284

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