A simplified LC-MS/MS method for the quantification of the cardiovascular disease biomarker trimethylamine-N-oxide and its precursors

A simplified LC-MS/MS method for the quantification of the cardiovascular disease biomarker trimethylamine-N-oxide and its precursors

Trimethylamine-N-oxide (TMAO) has emerged as a potential biomarker for atherosclerosis and the development of cardiovascular diseases (CVDs). Although several clinical studies have shown striking associations of TMAO levels with atherosclerosis and CVDs, TMAO determinations are not clinical routine...

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Bibliographic Details
Main Authors: Katharina Rox, Silke Rath, Dietmar H. Pieper, Marius Vital, Mark Brönstrup
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Journal of Pharmaceutical Analysis
Subjects:
TMAO
Atherosclerosis
Biomarker
Carnitine
Choline
Betaine
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177921000277

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http://www.sciencedirect.com/science/article/pii/S2095177921000277

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