Targeting Mitochondrial Dysfunction in Lung Diseases: Emphasis on Mitophagy

During mild stressful conditions, cells activate a multitude of mechanisms in an attempt to repair or re-establish homeostasis. One such mechanism is autophagic degradation of mitochondria or mitophagy to dispose damaged mitochondria. However, if stress persists beyond recovery then dysfunctional mi...

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Bibliographic Details
Main Authors: Sureshbabu eAngara, Vineet eBhandari
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00384/full