Prominent Striatum Amyloid Retention in Early-Onset Familial Alzheimer's Disease With PSEN1 Mutations: A Pilot PET/MR Study

Prominent Striatum Amyloid Retention in Early-Onset Familial Alzheimer's Disease With PSEN1 Mutations: A Pilot PET/MR Study

Background: With the advancements of amyloid imaging in recent years, this new imaging diagnostic method has aroused great interest from researchers. Till now, little is known regarding amyloid deposition specialty in patients with early-onset familial Alzheimer's disease (EOFAD), and even less...

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Bibliographic Details
Main Authors: Qi Qin, Liping Fu, Ruimin Wang, Jihui Lyu, Huixuan Ma, Minmin Zhan, Aihong Zhou, Fen Wang, Xiumei Zuo, Cuibai Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
early-onset familial Alzheimer's disease
PET/MR hybrid neuroimaging
amyloid deposition
striatum
Pittsburgh compound-B PET
cognitive performance
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.732159/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2021.732159/full

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