Cathelicidin preserves intestinal barrier function in polymicrobial sepsis

Cathelicidin preserves intestinal barrier function in polymicrobial sepsis

Abstract Objectives The intestinal epithelium compartmentalizes the sterile bloodstream and the commensal bacteria in the gut. Accumulating evidence suggests that this barrier is impaired in sepsis, aggravating systemic inflammation. Previous studies reported that cathelicidin is differentially expr...

Full description

Bibliographic Details
Main Authors: Jeffery Ho, Hung Chan, Yonghao Liang, Xiaodong Liu, Lin Zhang, Qing Li, Yuchen Zhang, Judeng Zeng, Felix N. Ugwu, Idy H. T. Ho, Wei Hu, Johnny C. W. Yau, Sunny H. Wong, Wai Tat Wong, Lowell Ling, Chi H. Cho, Richard L. Gallo, Tony Gin, Gary Tse, Jun Yu, Matthew T. V. Chan, Czarina C. H. Leung, William K. K. Wu
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Critical Care
Subjects:
LL-37
Sepsis
Bacterial translocation
Antimicrobial peptide
Online Access:https://doi.org/10.1186/s13054-020-2754-5

Internet

https://doi.org/10.1186/s13054-020-2754-5

Similar Items