Negative regulation of NF-κB by the ING4 tumor suppressor in breast cancer.

Negative regulation of NF-κB by the ING4 tumor suppressor in breast cancer.

Nuclear Factor kappa B (NF-κB) is a key mediator of normal immune response but contributes to aggressive cancer cell phenotypes when aberrantly activated. Here we present evidence that the Inhibitor of Growth 4 (ING4) tumor suppressor negatively regulates NF-κB in breast cancer. We surveyed primary...

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Bibliographic Details
Main Authors: Sara A Byron, Elizabeth Min, Tanya S Thal, Galen Hostetter, Aprill T Watanabe, David O Azorsa, Tanya H Little, Coya Tapia, Suwon Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23056468/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23056468/?tool=EBI

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