Upregulation of FOXM1 leads to diminished drug sensitivity in myeloma

Upregulation of FOXM1 leads to diminished drug sensitivity in myeloma

Abstract Background Following up on previous work demonstrating the involvement of the transcription factor forkhead box M1 (FOXM1) in the biology and outcome of a high-risk subset of newly diagnosed multiple myeloma (nMM), this study evaluated whether FOXM1 gene expression may be further upregulate...

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Bibliographic Details
Main Authors: Chunyan Gu, Xuefang Jing, Carol Holman, Ramakrishna Sompallae, Fenghuang Zhan, Guido Tricot, Ye Yang, Siegfried Janz
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Cancer
Subjects:
Plasma-cell neoplasm
Targeted cancer therapy
Small-drug inhibitor
Cellular senescence
Online Access:http://link.springer.com/article/10.1186/s12885-018-5015-0

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http://link.springer.com/article/10.1186/s12885-018-5015-0

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