99 Structural optimization of anti-CEA-GITR-CAR to reduce tonic signaling and improve antigen-specific reactivity
Main Authors: | Hiroshi Shiku, Yizheng Wang, Linan Wang, Takuma Kato |
---|---|
Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2020-11-01
|
Series: | Journal for ImmunoTherapy of Cancer |
Similar Items
-
Analytical and bioanalytical studies on Tc-99-radiolabelled anti-CEA monoclonal antibodies
by: Algaeer, Salma
Published: (1997) -
Tumor regression and immunity in combination therapy with anti-CEA chimeric antigen receptor T cells and anti-CEA-IL2 immunocytokine
by: Seung E. Cha, et al.
Published: (2021-01-01) -
Peritumoral administration of DRibbles-pulsed antigen-presenting cells enhances the antitumor efficacy of anti-GITR and anti-PD-1 antibodies via an antigen presenting independent mechanism
by: Jaina M. Patel, et al.
Published: (2019-11-01) -
The Role of GITR/GITRL Interaction in Autoimmune Diseases
by: Jie Tian, et al.
Published: (2020-10-01) -
Optimal target saturation of ligand-blocking anti-GITR antibody IBI37G5 dictates FcγR-independent GITR agonism and antitumor activity
by: Cao, L., et al.
Published: (2022)