MicroRNA-146a suppresses tumor malignancy via targeting vimentin in esophageal squamous cell carcinoma cells with lower fibronectin membrane assembly

MicroRNA-146a suppresses tumor malignancy via targeting vimentin in esophageal squamous cell carcinoma cells with lower fibronectin membrane assembly

Abstract Background Esophageal squamous cell carcinoma (ESCC) is widely prevalent in Taiwan, and high metastatic spread of ESCC leads to poor survival rate. Fibronectin (FN) assembly on the cell membrane may induce ESCC mobility. MicroRNAs (MiRNAs) are abundant in and participate in tumorigenesis in...

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Bibliographic Details
Main Authors: Hong-Yi Chang, Chi-Hua Lee, Yi-Syuan Li, Jing-Tong Huang, Sheng-Hui Lan, Yi-Fang Wang, Wu-Wei Lai, Yi-Ching Wang, Yan-Ju Lin, Hsiao-Sheng Liu, Hung-Chi Cheng
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Journal of Biomedical Science
Subjects:
ESCC
miR-146a
Vimentin
Cell migration
Invasion
Online Access:https://doi.org/10.1186/s12929-020-00693-4

Internet

https://doi.org/10.1186/s12929-020-00693-4

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