Increased proton-sensing receptor GPR4 signalling promotes colorectal cancer progression by activating the hippo pathwayResearch in context

Background: Colorectal cancer (CRC) is one of the high incidences tumours and is ranked second in cancer-related mortality. Even though great progress has been made, there are no effective therapeutic strategies for late stage and metastatic CRC patients. Acidity is one characteristic of the tumour...

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Bibliographic Details
Main Authors: Minhao Yu, Ran Cui, Yizhou Huang, Yang Luo, Shaolan Qin, Ming Zhong
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419306140