Perilipin-2 deletion promotes carbohydrate-mediated browning of white adipose tissue at ambient temperature

Mice lacking perilipin-2 (Plin2-null) are resistant to obesity, insulin resistance, and fatty liver induced by Western or high-fat diets. In the current study, we found that, compared with WT mice on Western diet, Plin2-null adipose tissue was more insulin sensitive and inguinal subcutaneous white a...

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Bibliographic Details
Main Authors: Andrew E. Libby, Elise S. Bales, Jenifer Monks, David J. Orlicky, James L. McManaman
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520330583