Perilipin-2 deletion promotes carbohydrate-mediated browning of white adipose tissue at ambient temperature
Mice lacking perilipin-2 (Plin2-null) are resistant to obesity, insulin resistance, and fatty liver induced by Western or high-fat diets. In the current study, we found that, compared with WT mice on Western diet, Plin2-null adipose tissue was more insulin sensitive and inguinal subcutaneous white a...
Main Authors: | Andrew E. Libby, Elise S. Bales, Jenifer Monks, David J. Orlicky, James L. McManaman |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-08-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520330583 |
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