The hepatic ectonucleotide pyrophosphatase/phosphodiesterase 1 gene mRNA abundance is reduced by insulin and induced by dexamethasone

Hormones regulate hepatic gene expressions to maintain metabolic homeostasis. Ectonucleotide pyrophosphatase/phosphodiesterase 1 has been thought to interfere with insulin signaling. To determine its potential role in the regulation of metabolism, we analyzed its gene (Enpp1) expression in the liver...

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Bibliographic Details
Main Authors: Huiwen Ma, Ping Wang, Dan Jin, Ting Jia, Hong Mao, Jiandi Zhang, Shi Zhao
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000400609&lng=en&tlng=en