Role of adaptor proteins in secretory granule biogenesis and maturation

In the regulated secretory pathway, secretory granules (SGs) store peptide hormones that are released on demand. SGs are formed at the trans-Golgi network (TGN) and must undergo a maturation process to become responsive to secretagogues. The production of mature SGs requires concentrating newly synt...

Full description

Bibliographic Details
Main Authors: Mathilde L Bonnemaison, Betty A Eipper, Richard E Mains
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-08-01
Series:Frontiers in Endocrinology
Subjects:
GGA
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00101/full