Fisetin Suppresses the Proliferation and Metastasis of Renal Cell Carcinoma through Upregulation of MEK/ERK-Targeting CTSS and ADAM9

Fisetin Suppresses the Proliferation and Metastasis of Renal Cell Carcinoma through Upregulation of MEK/ERK-Targeting CTSS and ADAM9

Fisetin, a natural flavonoid, is known to have anticarcinogenic effects against several cancers, but its role in mediating renal cell carcinoma (RCC) progression has not been delineated. Cell viability, cytotoxicity, and cell cycle distribution were measured using the 3‐(4,5‐cimethylthiazol‐2‐yl)‐2,...

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Bibliographic Details
Main Authors: Min-Hong Hsieh, Jen-Pi Tsai, Shun-Fa Yang, Hui-Ling Chiou, Chia-Liang Lin, Yi-Hsien Hsieh, Horng-Rong Chang
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
fisetin
CTSS
ADAM9
renal cell carcinoma
proliferation
migration
invasion
Online Access:https://www.mdpi.com/2073-4409/8/9/948

Internet

https://www.mdpi.com/2073-4409/8/9/948

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