Transcriptomic profiling of mTOR and ryanodine receptor signaling molecules in developing zebrafish in the absence and presence of PCB 95

The mechanistic target of rapamycin (mTOR) and ryanodine receptor (RyR) signaling pathways regulate fundamental processes of neurodevelopment, and genetic mutations within these pathways have been linked to neurodevelopmental disorders. While previous studies have established that these signaling mo...

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Bibliographic Details
Main Authors: Daniel F. Frank, Galen W. Miller, Richard E. Connon, Juergen Geist, Pamela J. Lein
Format: Article
Language:English
Published: PeerJ Inc. 2017-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/4106.pdf