The Genetics of Pemphigus Vulgaris

Pemphigus vulgaris (PV) is a severe autoimmune blistering disease caused by auto-antibodies (auto-Abs) directed against epithelial desmosomal components and leading to disruption of cell-cell adhesion. The exact mechanisms underlying the disease pathogenesis remain unknown and treatment is still bas...

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Bibliographic Details
Main Authors: Dan Vodo, Ofer Sarig, Eli Sprecher
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Medicine
Subjects:
HLA
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2018.00226/full