Palmitoylethanolamide Reduces Colon Cancer Cell Proliferation and Migration, Influences Tumor Cell Cycle and Exerts In Vivo Chemopreventive Effects

Palmitoylethanolamide Reduces Colon Cancer Cell Proliferation and Migration, Influences Tumor Cell Cycle and Exerts In Vivo Chemopreventive Effects

Palmitoylethanolamide (PEA) is an endogenous fatty acid amide related to the endocannabinoid anandamide. PEA exerts intestinal anti-inflammatory effects, but knowledge of its role in colon carcinogenesis is still largely fragmentary. We deepened this aspect by studying the effects of PEA (ultramicro...

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Bibliographic Details
Main Authors: Ester Pagano, Tommaso Venneri, Giuseppe Lucariello, Donatella Cicia, Vincenzo Brancaleone, M. Francesca Nanì, Nunzio A. Cacciola, Raffaele Capasso, Angelo A. Izzo, Francesca Borrelli, Barbara Romano
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
colon cancer
endocannabinoid system
acylethanolamides
Online Access:https://www.mdpi.com/2072-6694/13/8/1923

Internet

https://www.mdpi.com/2072-6694/13/8/1923

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