Strategies for identification of somatic variants using the Ion Torrent deep targeted sequencing platform

Strategies for identification of somatic variants using the Ion Torrent deep targeted sequencing platform

Abstract Background ‘Next-generation’ (NGS) sequencing has wide application in medical genetics, including the detection of somatic variation in cancer. The Ion Torrent-based (IONT) platform is among NGS technologies employed in clinical, research and diagnostic settings. However, identifying mutati...

Full description

Bibliographic Details
Main Authors: Aditya Deshpande, Wenhua Lang, Tina McDowell, Smruthy Sivakumar, Jiexin Zhang, Jing Wang, F. Anthony San Lucas, Jerry Fowler, Humam Kadara, Paul Scheet
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Bioinformatics
Subjects:
Next-generation sequencing
Ion torrent
Variant calling strategies
Ion Reporter
Varscan2
MuTect
Online Access:http://link.springer.com/article/10.1186/s12859-017-1991-3

Internet

http://link.springer.com/article/10.1186/s12859-017-1991-3

Similar Items