Systematically Characterizing A-to-I RNA Editing Neoantigens in Cancer

A-to-I RNA editing can contribute to the transcriptomic and proteomic diversity of many diseases including cancer. It has been reported that peptides generated from RNA editing could be naturally presented by human leukocyte antigen (HLA) molecules and elicit CD8+ T cell activation. However, a syste...

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Bibliographic Details
Main Authors: Chi Zhou, Zhiting Wei, Liye Zhang, Zhaoyi Yang, Qi Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.593989/full