Severe Malaria Infections Impair Germinal Center Responses by Inhibiting T Follicular Helper Cell Differentiation

Severe Malaria Infections Impair Germinal Center Responses by Inhibiting T Follicular Helper Cell Differentiation

Naturally acquired immunity to malaria develops only after years of repeated exposure to Plasmodium parasites. Despite the key role antibodies play in protection, the cellular processes underlying the slow acquisition of immunity remain unknown. Using mouse models, we show that severe malaria infect...

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Bibliographic Details
Main Authors: Victoria Ryg-Cornejo, Lisa Julia Ioannidis, Ann Ly, Chris Yu Chiu, Julie Tellier, Danika Lea Hill, Simon Peter Preston, Marc Pellegrini, Di Yu, Stephen Laurence Nutt, Axel Kallies, Diana Silvia Hansen
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715014187

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http://www.sciencedirect.com/science/article/pii/S2211124715014187

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