Development, Characterization and Cell Viability Inhibition of PVA Spheres Loaded with Doxorubicin and 4′-Amino-1-Naphthyl-Chalcone (D14) for Osteosarcoma

Development, Characterization and Cell Viability Inhibition of PVA Spheres Loaded with Doxorubicin and 4′-Amino-1-Naphthyl-Chalcone (D14) for Osteosarcoma

Chalcones (1,3-diaryl-2-propen-1-ones) are naturally occurring polyphenols with known anticancer activity against a variety of tumor cell lines, including osteosarcoma (OS). In this paper, we present the preparation and characterization of spheres (~2 mm) from polyvinyl alcohol (PVA) containing a co...

Full description

Bibliographic Details
Main Authors: Viviane Seba, Gabriel Goetten de Lima, Bruno L. Pereira, Gabriel Silva, Luiza Steffens Reinhardt, Pablo Ricardo Arantes, Bor Shin Chee, Mariana Bastos dos Santos, Suzelei C. França, Luis Octavio Regasini, Ana Lúcia Fachin, Zhi Cao, Michael J. D. Nugent, Mozart Marins
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Polymers
Subjects:
osteosarcoma
chalcone
doxorubicin
PVA
freeze–thaw
Online Access:https://www.mdpi.com/2073-4360/13/16/2611

Internet

https://www.mdpi.com/2073-4360/13/16/2611

Similar Items