Optimize the dose of oxaliplatin for locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy followed by radical surgery and adjuvant chemotherapy

Optimize the dose of oxaliplatin for locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy followed by radical surgery and adjuvant chemotherapy

Abstract Background Addition of oxaliplatin to capecitabine remains controversial for locally advanced rectal cancer (LARC). And cumulative oxaliplatin dose (COD) varied among clinical trials showing different therapeutic effects of this regimen. The objective of this study was to explore how COD af...

Full description

Bibliographic Details
Main Authors: Hui Chang, Ya-lan Tao, Wu Jiang, Chen Chen, Shi-liang Liu, Wei-jun Ye, Yuan-hong Gao
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Cancer
Subjects:
Rectal neoplasms
Oxaliplatin
Distant metastasis
Survival
Online Access:http://link.springer.com/article/10.1186/s12885-020-06988-x

Internet

http://link.springer.com/article/10.1186/s12885-020-06988-x

Similar Items