Autonomous interconversion between adult pancreatic α-cells and β-cells after differential metabolic challenges

Background: Evidence hints at the ability of β-cells to emerge from non-β-cells upon genetic or pharmacological interventions. However, their quantitative contributions to the process of autonomous β-cell regeneration without genetic or pharmacological manipulations remain to be determined. Methods...

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Bibliographic Details
Main Authors: Risheng Ye, Miao Wang, Qiong A. Wang, Stephen B. Spurgin, Zhao V. Wang, Kai Sun, Philipp E. Scherer
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877816300333