Association of P2Y12 Gene Promoter DNA Methylation with the Risk of Clopidogrel Resistance in Coronary Artery Disease Patients

Association of P2Y12 Gene Promoter DNA Methylation with the Risk of Clopidogrel Resistance in Coronary Artery Disease Patients

Background. Clopidogrel inhibits the ADP receptor P2Y12 to keep down the platelet aggregation. The goal of our study is to investigate the contribution of P2Y12 promoter DNA methylation to the risk of clopidogrel resistance (CR). Methods. The platelet functions were measured by the VerifyNow P2Y12 a...

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Bibliographic Details
Main Authors: Jia Su, Xiaojing Li, Qinglin Yu, Yahui Liu, Yaqing Wang, Haojun Song, Hanbin Cui, Weiping Du, Xiaohong Fei, Junsong Liu, Shaoyi Lin, Jian Wang, Wenyuan Zheng, Jinyan Zhong, Lulu Zhang, Maoqing Tong, Jin Xu, Xiaomin Chen
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/450814

Internet

http://dx.doi.org/10.1155/2014/450814

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