Mechanisms of metabonomic for a gateway drug: nicotine priming enhances behavioral response to cocaine with modification in energy metabolism and neurotransmitter level.

Mechanisms of metabonomic for a gateway drug: nicotine priming enhances behavioral response to cocaine with modification in energy metabolism and neurotransmitter level.

Nicotine, one of the most commonly used drugs, has become a major concern because tobacco serves as a gateway drug and is linked to illicit drug abuse, such as cocaine and marijuana. However, previous studies mainly focused on certain genes or neurotransmitters which have already been known to parti...

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Bibliographic Details
Main Authors: Hongyu Li, Qian Bu, Bo Chen, Xue Shao, Zhengtao Hu, Pengchi Deng, Lei Lv, Yi Deng, Ruiming Zhu, Yan Li, Baolai Zhang, Jing Hou, Changman Du, Qian Zhao, Dengqi Fu, Yinglan Zhao, Xiaobo Cen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3904956?pdf=render

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http://europepmc.org/articles/PMC3904956?pdf=render

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