The Synthesis and the Biological Evaluation of New Thiazolidin-4-one Derivatives Containing a Xanthine Moiety

The Synthesis and the Biological Evaluation of New Thiazolidin-4-one Derivatives Containing a Xanthine Moiety

Starting from theophylline (1,3-dimethylxanthine) new thiazolidin-4-one derivatives 7a1–7, 7b1–7 have been synthesized as potential antidiabetic drugs. The structure of the new derivatives was confirmed using spectral methods (FT-IR, 1H-NMR, 13C-NMR). The in vitro antioxidant potential of the synthe...

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Bibliographic Details
Main Authors: Lenuta Profire, Dan Lupascu, Liliana Foia, Florentina Geanina Lupascu, Oana Maria Dragostin
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:Molecules
Subjects:
thiazolidin-4-one
xanthine
synthesis
spectral methods
antioxidant effect
Online Access:http://www.mdpi.com/1420-3049/18/8/9684

Internet

http://www.mdpi.com/1420-3049/18/8/9684

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