Gene Augmentation and Editing to Improve TCR Engineered T Cell Therapy against Solid Tumors

Gene Augmentation and Editing to Improve TCR Engineered T Cell Therapy against Solid Tumors

Recent<b> </b>developments in gene engineering technologies have drastically improved the therapeutic treatment options for cancer patients. The use of effective chimeric antigen receptor T (CAR-T) cells and recombinant T cell receptor engineered T (rTCR-T) cells has entered the clinic f...

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Bibliographic Details
Main Authors: Vania Lo Presti, Frank Buitenwerf, Niek P. van Til, Stefan Nierkens
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Vaccines
Subjects:
adoptive T cell therapy
T cell receptor engineering
gene editing
solid tumors
Online Access:https://www.mdpi.com/2076-393X/8/4/733

Internet

https://www.mdpi.com/2076-393X/8/4/733

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