miR-301a Suppression within Fibroblasts Limits the Progression of Fibrosis through the TSC1/mTOR Pathway

miR-301a Suppression within Fibroblasts Limits the Progression of Fibrosis through the TSC1/mTOR Pathway

Pulmonary fibrosis has been characterized by abnormal proliferation of fibroblasts and massive deposition of the extracellular matrix, which results from a complex interplay of chronic injury and inflammatory responses. MicroRNA-301a (miR-301a) is activated by multiple inflammatory stimulators, cont...

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Bibliographic Details
Main Authors: Jiexuan Wang, Xun Li, Mingtian Zhong, Yansheng Wang, Liming Zou, Miaomiao Wang, Xiaoli Gong, Xinjie Wang, Chengzhi Zhou, Xiaodong Ma, Ming Liu
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
miR-301a
mTOR
pulmonary fibrosis
TSC1
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120301530

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http://www.sciencedirect.com/science/article/pii/S2162253120301530

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