The impact of different preanalytical methods related to CA 15-3 determination in frozen human blood samples: a systematic review

Abstract Background The determination of CA 15-3 is useful for monitoring breast cancer patients. Several retrospective studies determined CA 15-3 levels in frozen samples to evaluate the sensitivity and specificity of novel biomarkers in relation to breast cancer; however, freeze-thaw cycles, as we...

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Bibliographic Details
Main Authors: Luigi Coppola, Alessandra Cianflone, Katia Pane, Monica Franzese, Peppino Mirabelli, Marco Salvatore
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Systematic Reviews
Subjects:
Online Access:https://doi.org/10.1186/s13643-021-01631-7