CRIM1 complexes with ß-catenin and cadherins, stabilizes cell-cell junctions and is critical for neural morphogenesis.

In multicellular organisms, morphogenesis is a highly coordinated process that requires dynamically regulated adhesion between cells. An excellent example of cellular morphogenesis is the formation of the neural tube from the flattened epithelium of the neural plate. Cysteine-rich motor neuron prote...

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Bibliographic Details
Main Authors: Virgilio G Ponferrada, Jieqing Fan, Jefferson E Vallance, Shengyong Hu, Aygun Mamedova, Scott A Rankin, Matthew Kofron, Aaron M Zorn, Rashmi S Hegde, Richard A Lang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3299674?pdf=render