High Level Production of Monoclonal Antibodies Using an Optimized Plant Expression System

High Level Production of Monoclonal Antibodies Using an Optimized Plant Expression System

Biopharmaceuticals are a large and fast-growing sector of the total pharmaceutical market with antibody-based therapeutics accounting for over 100 billion USD in sales yearly. Mammalian cells are traditionally used for monoclonal antibody production, however plant-based expression systems have signi...

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Bibliographic Details
Main Authors: Andrew G. Diamos, Joseph G. L. Hunter, Mary D. Pardhe, Sun H. Rosenthal, Haiyan Sun, Bonnie C. Foster, Michelle P. DiPalma, Qiang Chen, Hugh S. Mason
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
plant-based biopharmaceuticals
pharming
transient expression
glycosylation
monoclonal antibodies
Zika virus
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00472/full

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https://www.frontiersin.org/article/10.3389/fbioe.2019.00472/full

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