Uncovering the Transmembrane Metal Binding Site of the Novel Bacterial Major Facilitator Superfamily-Type Copper Importer CcoA

Uptake and trafficking of metals and their delivery to their respective metalloproteins are important processes. Cells need precise control of each step to avoid exposure to excessive metal concentrations and their harmful consequences. Copper (Cu) is a required micronutrient used as a cofactor in p...

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Bibliographic Details
Main Authors: Bahia Khalfaoui-Hassani, Andreia F. Verissimo, Hans-Georg Koch, Fevzi Daldal
Format: Article
Language:English
Published: American Society for Microbiology 2016-01-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/1/e01981-15