In vivo evaluation of microglia activation by intracranial iron overload in central pain after spinal cord injury

In vivo evaluation of microglia activation by intracranial iron overload in central pain after spinal cord injury

Abstract Background Central pain (CP) is a common clinical problem in patients with spinal cord injury (SCI). Recent studies found the pathogenesis of CP was related to the remodeling of the brain. We investigate the roles of iron overload and subsequent microglia activate in the remodeling of the b...

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Bibliographic Details
Main Authors: Fan Xing Meng, Jing Ming Hou, Tian Sheng Sun
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Central pain
Spinal cord injury
Iron
Microglia
NF-κB
Online Access:http://link.springer.com/article/10.1186/s13018-017-0578-z

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http://link.springer.com/article/10.1186/s13018-017-0578-z

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