Tyrosine Phosphorylation of the K<sub>v</sub>2.1 Channel Contributes to Injury in Brain Ischemia

Tyrosine Phosphorylation of the K<sub>v</sub>2.1 Channel Contributes to Injury in Brain Ischemia

In brain ischemia, oxidative stress induces neuronal apoptosis, which is mediated by increased activity of the voltage-gated K<sup>+</sup> channel K<sub>v</sub>2.1 and results in an efflux of intracellular K<sup>+</sup>. The molecular mechanisms underlying the reg...

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Bibliographic Details
Main Authors: Min-Young Song, Ji Yeon Hwang, Eun Ji Bae, Saesbyeol Kim, Hye-Min Kang, Yong Jun Kim, Chan Park, Kang-Sik Park
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
K<sub>v</sub>2.1
tyrosine phosphorylation
brain ischemia
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/21/24/9538

Internet

https://www.mdpi.com/1422-0067/21/24/9538

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