Accelerated detection of mycolactone production and response to antibiotic treatment in a mouse model of Mycobacterium ulcerans disease.

Accelerated detection of mycolactone production and response to antibiotic treatment in a mouse model of Mycobacterium ulcerans disease.

Diagnosis of the neglected tropical disease, Buruli ulcer, can be made by acid-fast smear microscopy, specimen culture on mycobacterial growth media, polymerase chain reaction (PCR), and/or histopathology. All have drawbacks, including non-specificity and requirements for prolonged culture at 32°C,...

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Bibliographic Details
Main Authors: Paul J Converse, Yalan Xing, Ki Hyun Kim, Sandeep Tyagi, Si-Yang Li, Deepak V Almeida, Eric L Nuermberger, Jacques H Grosset, Yoshito Kishi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3879254?pdf=render

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http://europepmc.org/articles/PMC3879254?pdf=render

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