α-Chaconine Affects the Apoptosis, Mechanical Barrier Function, and Antioxidant Ability of Mouse Small Intestinal Epithelial Cells

α-Chaconine Affects the Apoptosis, Mechanical Barrier Function, and Antioxidant Ability of Mouse Small Intestinal Epithelial Cells

α-Chaconine is the most abundant glycoalkaloid in potato and toxic to the animal digestive system, but the mechanisms underlying the toxicity are unclear. In this study, mouse small intestinal epithelial cells were incubated with α-chaconine at 0, 0.4, and 0.8 μg/mL for 24, 48, and 72 h to examine a...

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Bibliographic Details
Main Authors: Yuhua He, Jiaqi Chen, Qiyue Zhang, Jialong Zhang, Lulai Wang, Xiaoxia Chen, Adrian J. Molenaar, Xuezhao Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Plant Science
Subjects:
α-chaconine
intestinal epithelial cell
cell cycle
cell apoptosis
mechanical barrier function
antioxidant ability
Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2021.673774/full

Internet

https://www.frontiersin.org/articles/10.3389/fpls.2021.673774/full

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