HLA-DR expression in clinical-grade bone marrow-derived multipotent mesenchymal stromal cells: a two-site study

HLA-DR expression in clinical-grade bone marrow-derived multipotent mesenchymal stromal cells: a two-site study

Abstract Background Contrary to the minimal criteria proposed by the International Society for Cell and Gene Therapy for defining multipotent mesenchymal stromal cells (MSC), human leukocyte antigen (HLA)-DR expression is largely unpredictable in ex vivo-expanded clinical-grade cultures. Although ac...

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Bibliographic Details
Main Authors: Marta Grau-Vorster, Anita Laitinen, Johanna Nystedt, Joaquim Vives
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Stem Cell Research & Therapy
Subjects:
Multipotent mesenchymal stromal cell
Potency
Identity
HLA-DR
Cellular therapy
Cell culture
Online Access:http://link.springer.com/article/10.1186/s13287-019-1279-9

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http://link.springer.com/article/10.1186/s13287-019-1279-9

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