Perinatal exposure to BDE-47 exacerbated autistic-like behaviors and impairments of dendritic development in a valproic acid-induced rat model of autism

Perinatal exposure to BDE-47 exacerbated autistic-like behaviors and impairments of dendritic development in a valproic acid-induced rat model of autism

Perinatal exposure to polybrominated diphenyl ethers (PBDEs) may be a potential risk factor for autism spectrum disorders (ASD). BDE-47 is one of the most common PBDEs and poses serious health hazards on the central nervous system (CNS). However, effects of perinatal exposure to BDE-47 on social beh...

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Bibliographic Details
Main Authors: Zixuan Li, Mingdan You, Xiaoyu Che, Yufeng Dai, Yuanyuan Xu, Yi Wang
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Polybrominated diphenyl ethers
Autism spectrum disorders
Dendritic development
BDNF-CREB signaling
Rats
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651321001111

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http://www.sciencedirect.com/science/article/pii/S0147651321001111

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