Biodegradable Stent with mTOR Inhibitor-Eluting Reduces Progression of Ureteral Stricture

Biodegradable Stent with mTOR Inhibitor-Eluting Reduces Progression of Ureteral Stricture

In this study, we investigated the effect of mTOR inhibitor (mTORi) drug-eluting biodegradable stent (DE stent), a putative restenosis-inhibiting device for coronary artery, on thermal-injury-related ureteral stricture in rabbits. In vitro evaluation confirmed the dose-dependent effect of mTORi, i.e...

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Bibliographic Details
Main Authors: Dong-Ru Ho, Shih-Horng Su, Pey-Jium Chang, Wei-Yu Lin, Yun-Ching Huang, Jian-Hui Lin, Kuo-Tsai Huang, Wai-Nga Chan, Chih-Shou Chen
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
ureter
drug-eluting stent
biodegradable
ureteral stricture
rapamycin
sirolimus
Online Access:https://www.mdpi.com/1422-0067/22/11/5664

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https://www.mdpi.com/1422-0067/22/11/5664

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