The Fibrosis and Immunological Features of Hypochlorous Acid Induced Mouse Model of Systemic Sclerosis

The Fibrosis and Immunological Features of Hypochlorous Acid Induced Mouse Model of Systemic Sclerosis

Fibrotic animal models are critical for the pathogenesis investigations and drug explorations in systemic sclerosis (SSc). The bleomycin (BLM)-induced mouse model is the classical and most widely used fibrosis model. However, traditional subcutaneous injection of BLM rarely induced diffuse skin and...

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Bibliographic Details
Main Authors: Meng Meng, Jieqiong Tan, Weilin Chen, Qian Du, Bin Xie, Nian Wang, Honglin Zhu, Kangkai Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
HOCl-induced mice
immune cell infiltration
pro-inflammatory mediators
fibrosis
SSc
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01861/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.01861/full

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