Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells.

Candida albicans is the most common cause of hematogenously disseminated and oropharyngeal candidiasis. Both of these diseases are characterized by fungal invasion of host cells. Previously, we have found that C. albicans hyphae invade endothelial cells and oral epithelial cells in vitro by inducing...

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Bibliographic Details
Main Authors: Quynh T Phan, Carter L Myers, Yue Fu, Donald C Sheppard, Michael R Yeaman, William H Welch, Ashraf S Ibrahim, John E Edwards, Scott G Filler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-03-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1802757?pdf=render