Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks

How factors involved in homologous recombination interact and function is a matter of interest. Here the authors use super-resolution imaging to describe the spatiotemporal dynamics of proteins associated with homologous recombination DNA repair in response to replication stress.

Bibliographic Details
Main Authors:	Donna R. Whelan, Wei Ting C. Lee, Yandong Yin, Dylan M. Ofri, Keria Bermudez-Hernandez, Sarah Keegan, David Fenyo, Eli Rothenberg
Format:	Article
Language:	English
Published:	Nature Publishing Group 2018-09-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-018-06435-3

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spelling	doaj-7dede67c47fa41e5b8e6f07d588a1c842021-05-11T09:39:22ZengNature Publishing GroupNature Communications2041-17232018-09-019111510.1038/s41467-018-06435-3Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forksDonna R. Whelan0Wei Ting C. Lee1Yandong Yin2Dylan M. Ofri3Keria Bermudez-Hernandez4Sarah Keegan5David Fenyo6Eli Rothenberg7Department of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineDepartment of Biochemistry and Molecular Pharmacology, Perlmutter Cancer Center, New York University School of MedicineHow factors involved in homologous recombination interact and function is a matter of interest. Here the authors use super-resolution imaging to describe the spatiotemporal dynamics of proteins associated with homologous recombination DNA repair in response to replication stress.https://doi.org/10.1038/s41467-018-06435-3
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Donna R. Whelan Wei Ting C. Lee Yandong Yin Dylan M. Ofri Keria Bermudez-Hernandez Sarah Keegan David Fenyo Eli Rothenberg
spellingShingle	Donna R. Whelan Wei Ting C. Lee Yandong Yin Dylan M. Ofri Keria Bermudez-Hernandez Sarah Keegan David Fenyo Eli Rothenberg Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks Nature Communications
author_facet	Donna R. Whelan Wei Ting C. Lee Yandong Yin Dylan M. Ofri Keria Bermudez-Hernandez Sarah Keegan David Fenyo Eli Rothenberg
author_sort	Donna R. Whelan
title	Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
title_short	Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
title_full	Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
title_fullStr	Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
title_full_unstemmed	Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
title_sort	spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2018-09-01
description	How factors involved in homologous recombination interact and function is a matter of interest. Here the authors use super-resolution imaging to describe the spatiotemporal dynamics of proteins associated with homologous recombination DNA repair in response to replication stress.
url	https://doi.org/10.1038/s41467-018-06435-3
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Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks

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