Analysis of the cartilage proteome from three different mouse models of genetic skeletal diseases reveals common and discrete disease signatures
Summary Pseudoachondroplasia and multiple epiphyseal dysplasia are genetic skeletal diseases resulting from mutations in cartilage structural proteins. Electron microscopy and immunohistochemistry previously showed that the appearance of the cartilage extracellular matrix (ECM) in targeted mouse mod...
Main Authors: | Peter A. Bell, Raimund Wagener, Frank Zaucke, Manuel Koch, Julian Selley, Stacey Warwood, David Knight, Raymond P. Boot-Handford, David J. Thornton, Michael D. Briggs |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2013-06-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/2/8/802 |
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